2003. 03 - 2009. 08: 성균관대학교 식품생명공학과 이학사
2009. 09 - 2011. 08: 서울대학교 식품생명공학과 농학석사
2012. 08 - 2017. 05: University of Illinois at Urbana Champaign, Food Science, Ph.D.
2011. 09. – 2012. 05: 서울대학교 농업생물신소재연구소, 연구원
2017. 06. – 2019. 01: University of Minnesota Twin Cities, Biotechnology Institute, Postdoc
2019. 02. – 2023. 01: 가톨릭대학교, 식품영양학과, 조교수
2023. 02. – 현재: 서울과학기술대학교, 식품공학과, 조교수
◾ Kang, M.J.*, Baek, K.R.*, Lee, Y.R.*, Kim, G.H., Seo, S.O. "Production of vitamin K in wild-type and engineered microorganisms". 2022, Microorganisms, doi.org/10.3390/microorganisms10030554.
◾ Seo, S.O., and Jin, Y.S. "Next-generation genetic and fermentation technologies for safe and sustainable production of food ingredients: Colors and flavorings". 2022, Annual Review of Food Science and Technology, doi.org/10.1146/annurev-food-052720-012228.
◾ Lee, Y.R.*, Bang, W.Y.*, Baek, K.R., Kim, G.H., Kang, M.J., Yang, J.#, Seo, S.O#. "Safety Evaluation by Phenotypic and Genomic Characterization of Four Lactobacilli Strains with Probiotic Properties". 2022, Microorganisms, doi.org/10.3390/microorganisms 10112218.
◾ Jung, J.Y., Kang, M.J., Hwang, H.S., Baek, K.R., Seo, S.O. "Reduction of Ethyl Carbamate in an Alcoholic Beverage by CRISPR/Cas9-Based Genome Editing of the Wild Yeast". 2022, Foods, doi.org/10.3390/foods12010102.
◾ Lee, W.H.*, Seo, S.O.*, Bae, Y.H., Nan, H., Jin, Y.S.#, Seo, J.H#. “Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes”. 2012, Bioprocess and Biosystems Engineering, doi: 10.1007/s00449-012-0736-y.
◾ Kim, S.J.*, Seo, S.O.*, Jin, Y.S.#, Seo, J.H.# “Production of 2,3-butanediol by engineered Saccharomyces cerevisiae”. 2013, Bioresource Technology, doi:10.1016/j.biotech.2013. 07.081.
◾ Kim, S.J., Seo, S.O., Park, Y.C., Jin, Y.S., Seo, J.H. “Production of 2,3-butanediol from xylose by engineered Saccharomyces cerevisiae”. 2014, Journal of Biotechnology, doi: 10.1016/j.jbiotec.2013.12.017.
◾ Nan, H., Seo, S.O., Oh, E.J., Seo, J.H., Cate, J.H.D., Jin, Y.S. “2,3-Butanediol production from cellobiose by engineered Saccharomyces cerevisiae”. 2014, Applied Microbiology and Biotechnology, doi: 10.1007/s00253-014-5683-x.
◾ Wang, Y., Zhang, Z.T., Seo, S.O., Choi, K., Lu, T., Jin, Y.S., Blascheck, H.P. “Markerless chromosomal gene deletion in Clostridium beijerinckii using CRISPR/Cas9 system”. 2014, Journal of Biotechnology, doi: 10.1016/j.jbiotec.2015.02.005.
◾ Kim, J.W., Seo, S.O., Zhang, G.C., Jin, Y.S., Seo, J.H. “Expression of Lactococcus lactis NADH oxidase increases 2,3-butanediol production in Pdc-deficient Saccharomyces cerevisiae”. 2015, Bioresource Technology, doi: 10.1016/j.biortech.2015.02.077.
◾ Liao, C., Seo, S.O., Celik, V., Liu, H., Kong, W., Wang, Y., Blaschek, H.P., Jin, Y.S., Lu, T. An integrated, systems metabolic picture of the acetone-butanol-ethanol fermentation by Clostridium acetobutylicum. 2015, Proceedings of the National Academy of Sciences, doi: 10.1073/pnas.1423143112.
◾ Wang, Y., Zhang, Z.T., Seo, S.O., Lynn, P., Lu, T., Jin, Y.S., Blaschek, H.P. “Bacterial genome editing with CRISPR-Cas9: deletion, integration, single nucleotide modification, and desirable clean mutant selection”. 2016, ACS Synthetic Biology, doi: 10.1021/acssynbio.6b00060.
◾ Liao, C., Seo, S.O., Lu, T. “System-level modeling of acetone-butanol-ethanol fermentation”. 2016, FEMS Microbiology Letters, doi: 10.1093/femsle/fnw074.
◾ Wang, Y., Zhang, Z.T., Seo, S.O., Lynn, P., Lu, T., Jin, Y.S., Blaschek, H.P. “Gene transcription repression in Clostridium beijerinckii using CRISPR-dCas9”. 2016 Biotechnology and Bioengineering, 113:2739-2743. doi: 10.1002/bit.26020.
◾ Choi, E.J., Kim, J.W, Kim, S.J., Seo, S.O., Lane, S., Park, Y.C., Jin, Y.S., Seo, J.H, “Enhanced production of 2,3-butanediol in pyruvate decarboxylase-deficient Saccharomyces cerevisiae through optimizing ratio of glucose/galactose”. 2016, Biotechnology Journal, doi: 10.1002/biot.201600042.
◾ Xia, P.F., Zhang, G.C., Walker, B., Seo, S.O., Kwak, S., Liu, J.J., Kim, H., Ort, D.R., Wang, S.G., Jin, Y.S. “Recycling carbon dioxide during xylose fermentation by engineered Saccharomyces cerevisiae”. 2016, ACS Synthetic biology, doi: 10.1021/acssynbio.6b00167.
◾ Kim, J.W., Kim, J.Y, Seo, S.O., Kim. K.H., Jin, Y.S., Seo, J.H, “Enhanced production of 2,3-butanediol by engineered Saccharomyces cerevisiae through fine-tuning of pyruvate decarboxylase and NADH oxidase activities”. 2016, Biotechnology for Biofuels, doi: 10.1186/s13068-016-0677-9.
◾ Seo, S.O., Wang, Y., Lu, T., Jin, Y.S., Blaschek, H.P. “Characterization of Clostridium beijerinckii spo0A mutant and its application to butyl butyrate production”. 2017, Biotechnology and Bioengineering, doi: 10.1002/bit.26057.
◾ Jang, Y.*, Seo, S.O.*, Kim, S.A., Kim, T.J., Kim, S.C., Jin, Y.S.#, Han, N.S.# “Elimination of the cryptic plasmid in Leuconostoc citreum by CRISPR/Cas9 system”. 2017, Journal of Biotechnology, doi: 10.1016/j.jbiotec.2017.04.018.
◾ Seo, S.O., Jenssen, H., Magis, A., Wang, Y., Lu, T., Price, N.D., Jin, Y.S.#, Blaschek, H.P#. “Genomic, transcriptional and phenotypic analysis of the glucose derepressed Clostridium beijerinckii mutant exhibiting acid crash phenotype”. 2017, Biotechnology Journal, doi: 10.1002/biot.201700182.
◾ Zhang, Z.T., P Jiménez-Bonilla, Seo, S.O., Lu, T., Jin, Y.S., Blaschek, H.P. Wang, Y. “Bacterial Genome Editing with CRISPR-Cas9: Taking Clostridium beijerinckii as an Example”. 2018, Methods in Molecular Biology, doi: 10.1007/978-1-4939-7795-6_17.
◾ Seo, S.O., Lu, T., Jin, Y.S.#, Blaschek, H.P.# “Development of an oxygen-independent flavin mononucleotide-based fluorescent reporter system in Clostridium beijerinckii and its potential applications”. 2018, Journal of Biotechnology, doi: 10.1016/j.jbiotec.2017.11.003.
◾ Seo, S.O., and Schmidt-Dannert, C. “Development of a synthetic cumate-inducible gene expression system in Bacillus”. 2019, Applied Microbiology and Biotechnology, doi: 10.1007/s00253-018-9485-4.
◾ Jang, Y., Kim, S.A., Seo, S.O., Li, L., Han, N.S. “Plasmid Curing Resulted in Improved Heterologous Gene Expression in Leuconostoc citreum EFEL2700”. 2019, Letters in Applied Microbiology, doi: 10.1111/lam.13118.
◾ Seo, S.O., Park, S.K., Jung, S.C., Ryu, C.M., Kim, J.S. "Anti-Contamination Strategies for Yeast Fermentations". 2020, Microorganisms, doi: 10.3390/microorganisms8020274.
◾ Yang, S.Y., Han, Y.H., Park, Y.L., Park, J.Y., No, S.Y., Jeong, D., Park, S., Park, H.Y., Kim, W., Seo, S.O.#, Yang, Y.H.# "Production of L-theanine using Escherichia coli whole-cell overexpressing γ- glutamylmethylamide synthetase with baker's yeast". 2020, Journal of Microbiology and Biotechnology, doi: 10.4014/jmb.1910.10044.
◾ Choi, T.R., Jeon, J.M., Bhatia, S.K., Gurav, R., Han, Y.H., Park, Y.L., Park, J.Y., Song, H., Park, H.Y., Yoon, J.J., Seo, S.O.#, Yang, Y.H.# "Production of low molecular weight P(3HB-co-3HV) by butyrate-acetoacetate CoA transferase (cftAB) in Escherichia coli". 2020, Biotechnology and Bioprocess Engineering, doi: 10.1007/s12257-019-0366-1.
◾ Kim, S.Y., Kim, S.A., Jang, Y., Seo, S.O.#, Han, N.S.# “Screening of endogenous strong promoters of Leuconostoc citreum EFEL2700 based on transcriptome analysis and its application for food-grade production of β-galactosidase ”. 2021, Journal of Biotechnology, doi: 10.1016/j.jbiotec.2020.12.001.
◾ Bhatia, S.K., Mehariya, S., Bhatia, R.K., Kumar, M., Pugazhendhi, A., Awasthi, M.K., Atabani, A.E., Kumar, G., Kim, W., Seo, S.O., Yang, Y.H., "Wastewater based microalgal biorefinery for bioenergy production: Progress and challenges". 2021, Science of The Total Environment, doi.org/10.1016/j.scitotenv.2020.141599.
◾ Song, H.S., Bhatia, S.K., Choi, T.R., Gurav, R., Kim, H.J., Lee, S.M., Park, S.L., Lee, H.S., Joo, H.S., Kim, W., Seo, S.O.#, Yang, Y.H.# "Increased Antibiotic Resistance of Methicillin-Resistant Staphylococcus aureus USA300 psm Mutants and a Complementation Study of psm Mutants Using Synthetic Phenol-Soluble Modulins". 2021, Journal of Microbiology and Biotechnology, doi.org/10.4014/jmb.2007.07034.
◾ Park, Y.L., Choi, T.R., Kim, H.J., Song, H.S., Lee, H.S., Park, S.L., Lee, S.M., Kim, S.H., Park, S., Bhatia, S.K., Gurav, R., Sung, C., Seo, S.O.#, Yang, Y.H.# "NaCl concentration-dependent aminoglycoside resistance of Halomonas socia CKY01 and identification of related genes". 2021, Journal of Microbiology and Biotechnology, doi.org/10.4014/jmb.2009.09017.
◾ Seo, S.O., Lu, T., Jin, Y.S., Blaschek, H.P. "A comparative phenotypic and genomic analysis of Clostridium beijerinckii mutant with enhanced solvent production". 2021, Journal of Biotechnology, doi.org/10.1016/j.jbiotec.2021.02.002.
◾ Yun, E.J. Seo, S.O., Kwak, S, Oh, E.J., Lee, S.H., Jin, Y.S., Kim, KH. "Fast filtration with a vacuum manifold system as a rapid and robust metabolome sampling method for Saccharomyces cerevisiae". 2021, Process Biochemistry, doi.org/10.1016/j.procbio.2021.08.012.
◾ Kang, S.Y.*, Pokhrel, A.*, Bratsch, S.*, Benson, J.J., Seo, S.O., Quin, M.B., Aksan, A. and Schmidt-Dannert, C. "Engineering Bacillus subtilis for the formation of a durable living biocomposite material". 2021, Nature Communications, doi.org/10.1038/s41467-021-27467-2.
◾ Kim, S.R.*, Kim, S.J.*, Kim, S.K*, Seo, S.O.*, Park, S., Shin, J., Kim, J.S., Park, B.R., Jin, Y.S., Chang, P.S., Park, Y.C.# "Yeast metabolic engineering for carbon dioxide fixation and its application". 2022, Bioresource Technology, doi.org/10.1016/j.biortech.2021.126349.
◾ Yeast cell wall mannan structural features, biological activities, and production strategies, Heliyon, vol.10 No.6 pp.1~17, 2024서승오
◾ Validating a Xylose Regulator to Increase Polyhydroxybutyrate Production for Utilizing Mixed Sugars from Lignocellulosic Biomass Using Escherichia coli, Journal of Microbiology and Biotechnology, vol.33 No.12 pp.1~10, 2023서승오
◾ “Applications of systems and synthetic biology in future food production”. 2019, KoSFoST international symposium and annual meeting, Songdo, Korea
◾ “Applications of microbial biotechnology for sustainable food production“. 2019, KSBB fall meeting and international symposium, Daegu, Korea
◾ "전통 누룩으로부터 분리한 신규 효모의 분석과 이를 이용한 막걸리 제조" . 2019, 학술제
◾ "발효식품에서 신규 유산균 발굴 및 특성화 연구" . 2019, 학술제
◾ "국내 기능성 당류 추세 현황 및 시장조사". 2019, 학술제
◾ "식물성 대체육과 육제품 품질 특성 비교". 2019, 학술제
◾“Reduction of ethyl carbamate in Makgeolli by brewing with engineered yeast". 2020, KMB 47th annual meeting and symposium, Korea
◾ "햄버거병 예방을 위한 식물성 패티의 제조 및 관능 향상 연구". 2020, 학술제
◾ "효모와 유산균이 함유된 사워도우 스타터와 이를 이용한 식빵 제조 연구". 2020, 학술제
◾ "바이오 생리활성 분야 국내외 유망기술 및 산업 동향 분석" 2021, KSBB Spring meeting and international symposium, Jeju, Korea
◾ "Ethyl carbamate reduction in Makgeolli by CRISPR/Cas9 based genome editing of industrial yeast isolated from Nuruk" 2021, KoSFoST international symposium and annual meeting, Daejeon, Korea
◾ "Enhanced flavors in Makgeolli using alcohol acetyltransferase-overexpressing Saccharomyces cerevisiae" 2021, KoSFoST international symposium and annual meeting, Daejeon, Korea
◾ "In vitro functional test of yeast cell extracts with different disruption and preparation methods" 2021, KoSFoST international symposium and annual meeting, Daejeon, Korea
◾ "Characterization of Bacillus velezensis strain isolated from Doenjang and its antifungal activity against Fusarium species" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "Isolation of Lactiplantibacillus plantarum from Kimchi for development of Korean sourdough starter culture" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "Comparison of immunomodulatory effects of the cell extracts from two different variants of Saccharomyces cerevisiae" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "Improved production of heme porphyrins in Bacillus megaterium by a cumate-inducible promoter" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "Evolutionary engineering of beneficial gut microorganisms for industrial-scale production of cell mass" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "Development of therapeutic probiotics for oral treatment of hyperuricemia" 2021, KSBB Fall meeting and international symposium, Gyeongju, Korea
◾ "김치 유래 유산균을 이용한 식물성 요거트 개발". 2021,학술제
◾ "관능성 특성 및 건강기능성이 강화된 홍삼 제조 연구". 2021, 학술제
◾ "곰팡이 항진균능을 가진 된장 유래 바실러스 활용 토마토 신선도 유지 연구". 2021, 학술제
◾ "식용곤충식품에 대한 관능평가 및 관능 개선 연구". 2021, 학술제
◾ "Evaluation of 2,3-butanediol production using sugarcane molasses by engineered Saccharomyces cerevisiae" 2022, KFN international symposium and annual meeting, Jeju, Korea
◾ "Development of engineered Leuconostoc citreum capable of degrading uric acid" 2022, KFN international symposium and annual meeting, Jeju, Korea
◾ "Yeast cell extracts from Saccharomyces cerevisiae promote immune response and phagocytosis in Raw 264.7 macrophages" 2022, KFN international symposium and annual meeting, Jeju, Korea
◾ "Improved heme production in engineered Bacillus megaterium by tight regulation of inducible system" 2022, KFN international symposium and annual meeting, Jeju, Korea
◾ "Development of next-generation probiotics and its application" 2022, KFN international symposium and annual meeting, Jeju, Korea
◾ "유당분해능을 지닌 김치 유산균을 활용한 사워크림치즈 제품 개발". 2022, 학술제
◾ "조직감 향상을 위한 해조류 이용 식물성 떡갈비 제조 연구". 2022, 학술제
◾ "전통주 유래 토종 효모를 이용한 지역특산 맥주 제조 연구". 2022, 학술제
◾ Kwang-Rim Baek, Geun-Hyung Kim, Seung-Oh Seo, Evaluation of Fermentation Conditions for Enhanced Heme Production by Engineered Bacillus megaterium, 2024 한국미생물생명공학회 제주 동계심포지엄, 제주 부영호텔&리조트, 2024서승오
◾ Ha-Neul Bae, Hye-Seon Hwang, Seung-Oh Seo, Secretory Production of Soybean Leghemoglobin by Engineered Yeast, 2024 한국미생물생명공학회 제주 동계심포지엄, 제주 부영호텔&리조트, 2024서승오
◾ Kwang-Rim Baek, Hye-Seon Hwang, Seung-Oh Seo, Anti-inflammatory effect of the cell extracts from Saccharomyces boulardii in LPS-induced Raw 264.7 macrophages, 2023 KFN International Symposium and Annual Meeting, Busan, BEXCO, 2023서승오
◾ Seung-Oh Seo, Use of microorganisms as functional foods and live biotherapeutic products, 2023 KoSFoST International Symposium and Annual Meeting, ICC Jeju, 2023서승오
◾ "Method of producing 2, 3-butanediol using recombinant yeast”. 2016, US Patent 등록
◾ "재조합 효모를 이용한 2,3-부탄다이올의 생산방법“. 2016, 한국특허청, 특허 등록
◾ "과채류를 이용한 유산균 발효식품 및 이의 제조방법" . 2019, 한국특허청, 특허 등록, 기술이전 완료
◾ "두류 및 곡류의 발효물을 포함하는 발효식품 및 이의 제조방법" . 2020, 한국특허청, 특허 출원, 기술이전 완료
◾ "발암물질이 저감화된 막걸리 효모 및 이를 이용한 막걸리의 제조 방법". 2021, 한국특허청, 특허 출원
◾ "재조합 균주 및 이를 이용한 대체육 식품 제조 방법". 2021, 한국특허청, 특허 출원
◾ "재조합 균주 및 이를 이용한 대체난 식품 제조 방법". 2021, 한국특허청, 특허 출원
◾ "카로티노이드 생산능이 있는 신규 미생물 균주 및 이의 용도". 2021, 한국특허청, 특허 출원, 기술이전 완료
◾ "산 분해능이 증대된 재조합 균주 및 이의 용도". 2022, 한국특허청, 특허 출원
◾ "해조류를 이용한 대체육 및 이의 제조방법". 2022, 한국특허청, 특허 출원, 기술이전 완료
◾ "트리코델마 리제이 균주를 이용한 재조합 단백질 발현 균주 제작방법". 2023, 한국특허청, 특허 출원
◾ "향미 고생산 효모 균주의 제작방법 및 이의 용도". 2023, 한국특허청, 특허 출원
◾ "형질전환된 재조합 균주와 이로부터 생성된 재조합 단백질 및 이의 제조방법". 2024, 한국특허청, 특허 출원
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